Human POMGNT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POMGNT1
Locus ID	55624
Kit Components	GA110833G1, POMGNT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110833G2, POMGNT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110833G3, POMGNT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001243766, NM_001290129, NM_001290130, NM_017739, NR_024332
Synonyms	gnT-I.2; GNTI.2; GnT I.2; LGMD2O; MEB; MGAT1.2; RP76
Summary	This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]

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