Human SPTLC3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPTLC3
Locus ID	55304
Kit Components	GA110690G1, SPTLC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110690G2, SPTLC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110690G3, SPTLC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_018327, NM_001349945
Synonyms	C20orf38; dJ718P11; dJ718P11.1; hLCB2b; LCB2B; LCB3; SPT3; SPTLC2L
Summary	This gene encodes a subunit of the serine palmitoyltransferase complex which catalyzes the rate-limiting step in sphingolipid biosynthesis. This subunit metabolizes lauroyl- and myristoyl-CoA and generates C14 and C16-sphingoid bases. [provided by RefSeq, Mar 2017]

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