Human ZCWPW1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZCWPW1
Locus ID	55063
Kit Components	GA110486G1, ZCWPW1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110486G2, ZCWPW1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110486G3, ZCWPW1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001258008, NM_017984
Synonyms	ZCW1
Summary	Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3) (PubMed:32744506, PubMed:20826339). Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs) (By similarity). Essential for male fertility and spermatogenesis (By similarity). Required for meiosis prophase I progression in male but not in female germ cells (By similarity).[UniProtKB/Swiss-Prot Function]

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