Human UCKL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UCKL1
Locus ID	54963
Kit Components	GA110409G1, UCKL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110409G2, UCKL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110409G3, UCKL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001193379, NM_017859, NR_126526, NM_001353475, NM_001353476, NM_001353477, NM_001353478, NM_001353479, NM_001353480, NM_001353481, NM_001353482, NR_148434, NR_148435, NR_148436, NR_148437, NR_148438, NR_148439, NR_148440, NR_148441, NR_148442
Synonyms	UCK1L; URKL1
Summary	The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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