Human Aprataxin (APTX) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	APTX
Locus ID	54840
Kit Components	GA110301G1, Aprataxin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110301G2, Aprataxin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110301G3, Aprataxin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001195248, NM_001195249, NM_001195250, NM_001195251, NM_001195252, NM_001195254, NM_017692, NM_175069, NM_175071, NM_175072, NM_175073, NR_036576, NR_036577, NR_036578, NR_036579, NM_001368995, NM_001368997, NM_001369000, NM_001369002, NM_001369004, NM_001369005, NM_001370670, NR_160920, NR_160922, NR_160923, NR_160930, NM_001368996, NM_001368998, NM_001368999, NM_001369001, NM_001369003, NM_001369006, NM_001370669, NM_001370673, NR_160921, NR_160924, NR_160925, NR_160926, NR_160927, NR_160928, NR_160929, NR_160931
Synonyms	AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
Summary	This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010]

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