Human MARCHF5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MARCHF5
Locus ID	54708
Kit Components	GA110225G1, MARCHF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110225G2, MARCHF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110225G3, MARCHF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017824
Synonyms	MARCH-V; MITOL; RNF153
Summary	MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008]

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