Human GPR85 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GPR85
Locus ID	54329
Kit Components	GA110080G1, GPR85 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110080G2, GPR85 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110080G3, GPR85 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146265, NM_001146266, NM_001146267, NM_018970
Synonyms	SREB; SREB2
Summary	Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]

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