Human TREM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TREM1
Locus ID	54210
Kit Components	GA110076G1, TREM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110076G2, TREM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110076G3, TREM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242589, NM_001242590, NM_018643, NR_136332
Synonyms	CD354; TREM-1
Summary	This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

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