Human MAP3K12 binding inhibitory protein 1 (MBIP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MBIP
Locus ID	51562
Kit Components	GA109876G1, MAP3K12 binding inhibitory protein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109876G2, MAP3K12 binding inhibitory protein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109876G3, MAP3K12 binding inhibitory protein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001144891, NM_001308110, NM_016586
Synonyms	MAP3K12 binding inhibitory protein 1; MUK-binding inhibitory protein; OTTHUMP00000178844
Summary	Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.[UniProtKB/Swiss-Prot Function]

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