Human PPHLN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPHLN1
Locus ID	51535
Kit Components	GA109860G1, PPHLN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109860G2, PPHLN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109860G3, PPHLN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001143787, NM_001143788, NM_001143789, NM_016488, NM_201438, NM_201439, NM_201440, NM_201515, NM_001364829, NM_001364823, NM_001364824, NM_001364825, NM_001364827, NM_001364828, NM_001364830, NM_001364831, NM_001364833, NM_001364822, NM_001364826, NM_001364832, NM_001364834
Synonyms	CR; HSPC206; HSPC232
Summary	The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.