Human Archaemetzincin 2 (AMZ2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AMZ2
Locus ID	51321
Kit Components	GA109740G1, Archaemetzincin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109740G2, Archaemetzincin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109740G3, Archaemetzincin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033569, NM_001033570, NM_001033571, NM_001033572, NM_001033574, NM_001289054, NM_001289056, NM_016627, NM_001346471, NM_001346472, NM_001346473, NM_001346474, NM_001346475, NM_001346476, NM_001346477, NM_001346478, NM_001346479, NM_001346480, NM_001346481, NM_001346482, NM_001346483, NM_001346484, NM_001346485, NR_144442, NR_144443
Synonyms	archaelysin family metallopeptidase 2; archaemetzincin-2; archaemetzincins-2
Summary	The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]

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