Human CLEC1B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CLEC1B
Locus ID	51266
Kit Components	GA109689G1, CLEC1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109689G2, CLEC1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109689G3, CLEC1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001099431, NM_016509
Synonyms	1810061I13Rik; CLEC2; CLEC2B; PRO1384; QDED721
Summary	Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]

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