Human NAGPA activation kit by CRISPRa
CAT#: GA109624
NAGPA CRISPRa kit - CRISPR gene activation of human N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | NAGPA |
Locus ID | 51172 |
Kit Components | GA109624G1, NAGPA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109624G2, NAGPA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109624G3, NAGPA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_016256 |
Synonyms | APAA; UCE |
Summary | Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. The encoded preproprotein is proteolytically processed by furin to generate the mature enzyme, a homotetramer of two disulfide-linked homodimers. Mutations in this gene are associated with developmental stuttering in human patients. [provided by RefSeq, Oct 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN418271 | NAGPA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |