Human TRNT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRNT1
Locus ID	51095
Kit Components	GA109559G1, TRNT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109559G2, TRNT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109559G3, TRNT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001302946, NM_016000, NM_182916, NM_001367321, NM_001367323, NR_159934, NR_159937, NR_159938, NR_159939, NR_159940, NR_159943, NM_001367322, NR_159935, NR_159936, NR_159941, NR_159942, NR_159944
Synonyms	CCA1; CGI-47; MtCCA; SIFD
Summary	The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

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