Human Adiponectin Receptor 1 (ADIPOR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADIPOR1
Locus ID	51094
Kit Components	GA109558G1, Adiponectin Receptor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109558G2, Adiponectin Receptor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109558G3, Adiponectin Receptor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001127687, NM_001290553, NM_001290557, NM_001290629, NM_015999, NR_046083
Synonyms	ACDCR1; CGI-45; CGI45; FLJ25385; FLJ42464; PAQR1; TESBP1A
Summary	This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]

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