Human MEMO1 activation kit by CRISPRa

CAT#: GA109538

MEMO1 CRISPRa kit - CRISPR gene activation of human mediator of cell motility 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-NCDN Antibody
    • 100 ul

CNY 5,250.00


MEMO1 (Myc-DDK-tagged)-Human mediator of cell motility 1 (MEMO1), transcript variant 1
    • 10 ug

CNY 2,400.00
CNY 3,990.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MEMO1
Locus ID 51072
Kit Components

GA109538G1, MEMO1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109538G2, MEMO1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109538G3, MEMO1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001137602, NM_001301833, NM_001301852, NM_015955, NR_126032, NR_126034
Synonyms C2orf4; CGI-27; MEMO; NS5ATP7
Summary May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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