Human EXOSC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EXOSC1
Locus ID	51013
Kit Components	GA109497G1, EXOSC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109497G2, EXOSC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109497G3, EXOSC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318362, NM_001318363, NM_001318364, NM_001318365, NM_001318366, NM_016046, NR_134586, NR_134587, N34159
Synonyms	CGI-108; CSL4; Csl4p; hCsl4p; p13; SKI4; Ski4p
Summary	This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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