Human DNA polymerase mu (POLM) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POLM
Locus ID	27434
Kit Components	GA109148G1, DNA polymerase mu gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109148G2, DNA polymerase mu gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109148G3, DNA polymerase mu gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001284330, NM_001284331, NM_013284, NR_104299, NR_156112, NR_156113, NM_001362683
Synonyms	Pol Mu; Tdt-N
Summary	Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.[UniProtKB/Swiss-Prot Function]

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