Human HTRA2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HTRA2
Locus ID	27429
Kit Components	GA109145G1, HTRA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109145G2, HTRA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109145G3, HTRA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013247, NM_145074, NM_001321727, NM_001321728, NR_135769, NR_135770, NR_135771, NR_135772
Synonyms	OMI; PARK13; PRSS25
Summary	This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

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