Human cvHSP (HSPB7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSPB7
Locus ID	27129
Kit Components	GA109025G1, cvHSP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109025G2, cvHSP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109025G3, cvHSP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_014424, NM_001349682, NM_001349683, NM_001349685, NM_001349686, NM_001349687, NM_001349688, NM_001349689
Synonyms	cvHSP
Summary	This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma. [provided by RefSeq, Mar 2017]

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