Human AFF4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AFF4
Locus ID	27125
Kit Components	GA109022G1, AFF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109022G2, AFF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109022G3, AFF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014423
Synonyms	AF5Q31; MCEF
Summary	The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]

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