Human APPL (APPL1) activation kit by CRISPRa
CAT#: GA108731
APPL1 CRISPRa kit - CRISPR gene activation of human adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
CNY 12,255.00
Cited in 1 publication. |
CNY 1,999.00
CNY 2,700.00
CNY 5,192.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | APPL1 |
Locus ID | 26060 |
Kit Components | GA108731G1, APPL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108731G2, APPL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108731G3, APPL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_012096 |
Synonyms | APPL; DIP13alpha; MODY14 |
Summary | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this Gene Expression has been cited in the following citations: |
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APPL1 promotes glucose uptake in response to mechanical stretch via the PKCζ-non-muscle myosin IIa pathway in C2C12 myotubes.
,null,
Cellular signalling
,PubMed ID 27478065
[APPL1]
|
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
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KN406021 | APPL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |