Human SH2B1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH2B1
Locus ID	25970
Kit Components	GA108664G1, SH2B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108664G2, SH2B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108664G3, SH2B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145795, NM_001145796, NM_001145797, NM_001145812, NM_001308293, NM_001308294, NM_015503
Synonyms	PSM; SH2B
Summary	This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

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