Human POT1 activation kit by CRISPRa

CAT#: GA108626

POT1 CRISPRa kit - CRISPR gene activation of human protection of telomeres 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
POT1 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


POT1 (Myc-DDK-tagged)-Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 1
    • 10 ug

CNY 4,720.00


POT1 Rabbit monoclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol POT1
Locus ID 25913
Kit Components

GA108626G1, POT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108626G2, POT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108626G3, POT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001042594, NM_015450, NR_003102, NR_003103, NR_003104
Synonyms CMM10; GLM9; HPOT1
Summary This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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