Human SPDEF activation kit by CRISPRa
CAT#: GA108548
SPDEF CRISPRa kit - CRISPR gene activation of human SAM pointed domain containing ETS transcription factor
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SPDEF |
Locus ID | 25803 |
Kit Components | GA108548G1, SPDEF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108548G2, SPDEF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108548G3, SPDEF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001252294, NM_012391 |
Synonyms | bA375E1.3; PDEF |
Summary | The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN405688 | SPDEF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |