Human TACI (TNFRSF13B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNFRSF13B
Locus ID	23495
Kit Components	GA108343G1, TACI gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108343G2, TACI gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108343G3, TACI gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012452
Synonyms	CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF14B
Summary	The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

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