Human LEPROTL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LEPROTL1
Locus ID	23484
Kit Components	GA108339G1, LEPROTL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108339G2, LEPROTL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108339G3, LEPROTL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001128208, NM_015344
Synonyms	HSPC112; my047; Vps55
Summary	Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.[UniProtKB/Swiss-Prot Function]

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