Human DULLARD (CTDNEP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTDNEP1
Locus ID	23399
Kit Components	GA108279G1, DULLARD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108279G2, DULLARD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108279G3, DULLARD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143775, NM_015343
Synonyms	DULLARD; HSA011916; NET56
Summary	Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.[UniProtKB/Swiss-Prot Function]

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