Human USP22 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP22
Locus ID	23326
Kit Components	GA108221G1, USP22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108221G2, USP22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108221G3, USP22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015276
Synonyms	USP3L
Summary	Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.[UniProtKB/Swiss-Prot Function]

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