Human PHLPP (PHLPP1) activation kit by CRISPRa

CAT#: GA108152

PHLPP1 CRISPRa kit - CRISPR gene activation of human PH domain and leucine rich repeat protein phosphatase 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal PHLPP1 Antibody
    • 100 ug

CNY 5,808.00


PHLPP1 (Myc-DDK-tagged)-Human PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1)
    • 10 ug

CNY 8,392.00


PHLPP1 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PHLPP1
Locus ID 23239
Kit Components

GA108152G1, PHLPP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108152G2, PHLPP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108152G3, PHLPP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_194449
Synonyms PHLPP; PLEKHE1; PPM3A; SCOP
Summary This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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