Human DBC2 (RHOBTB2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RHOBTB2
Locus ID	23221
Kit Components	GA108138G1, DBC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108138G2, DBC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108138G3, DBC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160036, NM_001160037, NM_015178
Synonyms	DBC2
Summary	The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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