Human HECW1 activation kit by CRISPRa
CAT#: GA108016
HECW1 CRISPRa kit - CRISPR gene activation of human HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
CNY 12,255.00
CNY 10,992.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HECW1 |
Locus ID | 23072 |
Kit Components | GA108016G1, HECW1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108016G2, HECW1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108016G3, HECW1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001287059, NM_015052 |
Synonyms | NEDL1 |
Summary | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN413181 | HECW1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |