Human ATF7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATF7
Locus ID	11016
Kit Components	GA107566G1, ATF7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107566G2, ATF7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107566G3, ATF7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130059, NM_001130060, NM_001206682, NM_001206683, NM_006856, NR_073163, NM_001366561, NM_001366563, NM_001366555, NM_001366556, NM_001366558, NM_001366562
Synonyms	ATFA
Summary	Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.[UniProtKB/Swiss-Prot Function]

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