Human Mitofilin (IMMT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IMMT
Locus ID	10989
Kit Components	GA107545G1, Mitofilin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107545G2, Mitofilin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107545G3, Mitofilin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001100169, NM_001100170, NM_006839
Synonyms	HMP; Mic60; MINOS2; P87; P87/89; P89; PIG4; PIG52
Summary	Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).[UniProtKB/Swiss-Prot Function]

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