Human RUVBL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RUVBL2
Locus ID	10856
Kit Components	GA107433G1, RUVBL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107433G2, RUVBL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107433G3, RUVBL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006666, NM_001321190, NM_001321191, NR_135578
Synonyms	CGI-46; ECP51; INO80J; REPTIN; RVB2; TIH2; TIP48; TIP49B
Summary	This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008]

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