Human SA2 (STAG2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STAG2
Locus ID	10735
Kit Components	GA107355G1, SA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107355G2, SA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107355G3, SA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042749, NM_001042750, NM_001042751, NM_001282418, NM_006603
Synonyms	bA517O1.1; SA-2; SA2; SCC3B
Summary	The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

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