Human ATP dependent metalloprotease YME1L1 (YME1L1) activation kit by CRISPRa

CAT#: GA107351

YME1L1 CRISPRa kit - CRISPR gene activation of human YME1 like 1 ATPase



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
YME1L1 mouse monoclonal antibody, clone OTI2G10 (formerly 2G10)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


YME1L1 (Myc-DDK-tagged)-Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3
    • 10 ug

CNY 5,248.00


YME1L1 mouse monoclonal antibody, clone OTI4E3 (formerly 4E3)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol YME1L1
Locus ID 10730
Kit Components

GA107351G1, ATP dependent metalloprotease YME1L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107351G2, ATP dependent metalloprotease YME1L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107351G3, ATP dependent metalloprotease YME1L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001253866, NM_014263, NM_139312, NM_139313
Synonyms FTSH; MEG4; PAMP; YME1L
Summary The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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