Human AMSH (STAMBP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STAMBP
Locus ID	10617
Kit Components	GA107270G1, AMSH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107270G2, AMSH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107270G3, AMSH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_006463, NM_201647, NM_213622, NM_001353967, NM_001353968, NM_001353969, NM_001353970, NM_001353971, NM_001353972, NM_001353973, NM_001353974, NM_001353975, NM_001353976, NR_148668, NR_148669, NR_148670, NR_148671
Synonyms	AMSH; MICCAP
Summary	Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]

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