Human ERLIN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERLIN1
Locus ID	10613
Kit Components	GA107266G1, ERLIN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107266G2, ERLIN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107266G3, ERLIN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001100626, NM_006459, NM_001347856, NM_001347857, NM_001347858, NM_001347859, NM_001347860, NM_001347861, NR_144755, NR_144756, NR_144757, NR_144758, NR_144759, NR_144760
Synonyms	C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62
Summary	The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.