Human SMC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SMC2
Locus ID	10592
Kit Components	GA107249G1, SMC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107249G2, SMC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107249G3, SMC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042550, NM_001042551, NM_001265602, NM_006444
Synonyms	CAP-E; CAPE; SMC-2; SMC2L1
Summary	Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.[UniProtKB/Swiss-Prot Function]

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