Human SIVA (SIVA1) activation kit by CRISPRa

CAT#: GA107231

SIVA1 CRISPRa kit - CRISPR gene activation of human SIVA1 apoptosis inducing factor



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SIVA1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


SIVA1 (Myc-DDK-tagged)-Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1
    • 10 ug

CNY 2,400.00
CNY 3,705.00


SIVA1 mouse monoclonal antibody, clone OTI2B7 (formerly 2B7)
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SIVA1
Locus ID 10572
Kit Components

GA107231G1, SIVA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107231G2, SIVA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107231G3, SIVA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_006427, NM_021709
Synonyms CD27BP; SIVA; Siva-1; Siva-2
Summary This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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