Human ARFGEF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARFGEF2
Locus ID	10564
Kit Components	GA107224G1, ARFGEF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107224G2, ARFGEF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107224G3, ARFGEF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006420
Synonyms	BIG2; dJ1164I10.1; PVNH2
Summary	ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]

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