Human Cyclophilin E (PPIE) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPIE
Locus ID	10450
Kit Components	GA107127G1, Cyclophilin E gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107127G2, Cyclophilin E gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107127G3, Cyclophilin E gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001195007, NM_001319293, NM_006112, NM_203456, NM_203457, NR_036543, NR_036544
Synonyms	CYP-33; CYP33
Summary	The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]

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