Human TRK fused gene (TFG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TFG
Locus ID	10342
Kit Components	GA107048G1, TRK fused gene gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107048G2, TRK fused gene gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107048G3, TRK fused gene gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001007565, NM_001195478, NM_001195479, NM_006070
Synonyms	HMSNP; SPG57; TF6; TRKT3
Summary	There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]

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