Human USPL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USPL1
Locus ID	10208
Kit Components	GA106938G1, USPL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106938G2, USPL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106938G3, USPL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001321532, NM_001321533, NM_001321534, NM_005800
Synonyms	bA121O19.1; C13orf22; D13S106E
Summary	SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms (PubMed:22878415). Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (PubMed:24413172). Is a component of complexes that can bind to U snRNA genes (PubMed:24413172).[UniProtKB/Swiss-Prot Function]

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