Human Elastase 3A (CELA3A) activation kit by CRISPRa
CAT#: GA106879
CELA3A CRISPRa kit - CRISPR gene activation of human chymotrypsin like elastase 3A
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CELA3A |
Locus ID | 10136 |
Kit Components | GA106879G1, Elastase 3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106879G2, Elastase 3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106879G3, Elastase 3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_005747 |
Synonyms | ELA3; ELA3A |
Summary | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN403249 | CELA3A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |