Human LRPPRC activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LRPPRC
Locus ID	10128
Kit Components	GA106872G1, LRPPRC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106872G2, LRPPRC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106872G3, LRPPRC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133259
Synonyms	CLONE-23970; GP130; LRP130; LSFC
Summary	This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]

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