Human RABGAP1L activation kit by CRISPRa

CAT#: GA106696

RABGAP1L CRISPRa kit - CRISPR gene activation of human RAB GTPase activating protein 1 like



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-RABGAP1L Antibody
    • 100 ul

CNY 5,250.00


RABGAP1L (Myc-DDK-tagged)-Human RAB GTPase activating protein 1-like (RABGAP1L), transcript variant 1
    • 10 ug

CNY 5,968.00
CNY 8,650.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol RABGAP1L
Locus ID 9910
Kit Components

GA106696G1, RABGAP1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106696G2, RABGAP1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106696G3, RABGAP1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001035230, NM_001243763, NM_001243764, NM_001243765, NM_014857, NM_001330989, NM_001366445, NM_001366447, NM_001366448, NM_001366451, NM_001366452, NM_001366453, NM_001366457, NR_158982, NM_001366446, NM_001366449, NM_001366450, NM_001366454, NM_001366455, NM_001366456, NR_158981
Synonyms HHL; TBC1D18
Summary GTP-hydrolysis activating protein (GAP) for small GTPase RAB22A, converting active RAB22A-GTP to the inactive form RAB22A-GDP (PubMed:16923123). Plays a role in endocytosis and intracellular protein transport. Recruited by ANK2 to phosphatidylinositol 3-phosphate (PI3P)-positive early endosomes, where it inactivates RAB22A, and promotes polarized trafficking to the leading edge of the migrating cells. Part of the ANK2/RABGAP1L complex which is required for the polarized recycling of fibronectin receptor ITGA5 ITGB1 to the plasma membrane that enables continuous directional cell migration (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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