Human RGP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RGP1
Locus ID	9827
Kit Components	GA106623G1, RGP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106623G2, RGP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106623G3, RGP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080496, NM_014785
Synonyms	KIAA0258
Summary	The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.[UniProtKB/Swiss-Prot Function]

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