Human Semaphorin 3E (SEMA3E) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SEMA3E
Locus ID	9723
Kit Components	GA106531G1, Semaphorin 3E gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106531G2, Semaphorin 3E gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106531G3, Semaphorin 3E gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001178129, NM_012431
Synonyms	coll-5; M-SEMAH; M-SemaK; SEMAH
Summary	Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

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